CHRM2 polyclonal antibody
产品名称: CHRM2 polyclonal antibody
英文名称: CHRM2 polyclonal antibody
产品编号: PAB25473
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of CHRM2.
- Immunogen:
- A synthetic peptide corresponding to amino acids 352-364 at internal region of human CHRM2.
- Sequence:
- CQNGDEKQNIVARK
- Host:
- Goat
- Theoretical MW (kDa):
- 50
- Reactivity:
- Mouse
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:128000)
Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 1129
- Protein Accession#:
- NP_000730.1
- Gene Name:
- CHRM2
- Gene Alias:
- FLJ43243,HM2,MGC120006,MGC120007
- Gene Description:
- cholinergic receptor, muscarinic 2
- Omim ID:
- 118493
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq
- Other Designations:
- 7TM receptor,cholinergic receptor, muscarinic 2, isoform a,muscarinic M2 receptor,muscarinic acetylcholine receptor M2
- Related Disease
- Alcoholism
- Alzheimer Disease
- Alzheimer disease
- Asthma
- Asthma
- Bipolar Disorder
- Cardiomyopathy, Dilated
- Cardiovascular Diseases
- Cognition
- Depressive Disorder
- Depressive Disorder, Major
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Edema
- Genetic Predisposition to Disease
- Heart Diseases
- Hypercholesterolemia
- Inflammation
- Mental Disorders