ABCC12 monoclonal antibody, clone M9II-3
产品名称： ABCC12 monoclonal antibody, clone M9II-3
英文名称： ABCC12 monoclonal antibody, clone M9II-3
产品编号： MAB6675
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rat monoclonal antibody raised against partial recombinant ABCC12.
- Immunogen:
- Recombinant protein corresponding to amino acids 690-734 of human ABCC12.
- Host:
- Rat
- Reactivity:
- Human
- Specificity:
- M9II-3 reacts with an internal epitope of MRP9 (ABCC12), an approximately 150 kD transmembrane protein that is related to the multidrug resistance protein MRP1
- Form:
- Liquid
- Isotype:
- IgG
- Storage Buffer:
- In serum-free culture supernatant (0.7% BSA, 0.1% sodium azide)
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- Immunohistochemistry (Frozen sections) (1:20)
Immunocytochemistry (1:20-1:50)
Wstern Blot (1:20-1:50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Multidrug resistance-associated protein 9 (ABCC12) is present in mouse and boar sperm.
Ono N, Van der Heijden I, Scheffer GL, Van de Wetering K, Van Deemter E, De Haas M, Boerke A, Gadella BM, De Rooij DG, Neefjes JJ, Groothuis TA, Oomen L, Brocks L, Ishikawa T, Borst P.Ono N, Van der Heijden I, Scheffer GL, Van de Wetering K, Van Deemter E, De Haas M, Boerke A, Gadella BM, De Rooij DG, Neefjes JJ, Groothuis TA, Oomen L, Brocks L, Ishikawa T, Borst P.
- 2.
- ABCC10, ABCC11, and ABCC12.
Kruh GD, Guo Y, Hopper-Borge E, Belinsky MG, Chen ZS.Kruh GD, Guo Y, Hopper-Borge E, Belinsky MG, Chen ZS.
- 3.
- MRP9, an unusual truncated member of the ABC transporter superfamily, is highly expressed in breast cancer.
Bera TK, Iavarone C, Kumar V, Lee S, Lee B, Pastan I.Bera TK, Iavarone C, Kumar V, Lee S, Lee B, Pastan I.
- Application Image
- Western Blot
- Immunohistochemistry (Frozen sections)
- Immunocytochemistry
- Entrez GeneID:
- 94160
- Gene Name:
- ABCC12
- Gene Alias:
- MGC27071,MRP9
- Gene Description:
- ATP-binding cassette, sub-family C (CFTR/MRP), member 12
- Omim ID:
- 607041
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq
- Other Designations:
- ATP-binding cassette protein C12,ATP-binding cassette transporter sub-family C member 12,OTTHUMP00000164186,multidrug resistance-associated protein 9
- Gene Pathway
- Related Disease